1. High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy.
    Hathaway CK, Chang AS, Grant R, Kim HS, Madden VJ, Bagnell CR Jr, Jennette JC, Smithies O, Kakoki M.
    Proc Natl Acad Sci U S A. 2016 February 23; 113(8): 2218–2222. Published online 2016 February 8. doi: 10.1073/pnas.1600511113
    PMID: 26858454 PMCID: PMC4776516
  2. A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions.
    Lawrence M, Testen A, Koklic T, Smithies O.
    J Vis Exp. 2016; (108): 53388. Published online 2016 February 5. doi: 10.3791/53388
    PMID: 26890032 PMCID: PMC4781725
  3. A conversation with Oliver Smithies.
    Smithies O, Coffman T.
    Annu Rev Physiol. 2015;77:1-11. doi: 10.1146/annurev-physiol-021014-071806.
    PMID: 25668016
  4. Transforming growth factor β1 and diabetic nephropathy.
    Chang AS, Hathaway CK, Smithies O, Kakoki M.
    Am J Physiol Renal Physiol. 2015 Dec 30:ajprenal.00502.2015. doi: 10.1152/ajprenal.00502.2015. [Epub ahead of print] PMID: 26719364 PMCID: PMC4835922
  5. A conversation with Oliver Smithies.
    Smithies O, Neill US.
    J Clin Invest. 2015 Nov 2;125(11):3997-8. doi: 10.1172/JCI84087. Epub 2015 Nov 2. No abstract available.
    PMID: 26524588
  6. The Whole of a Scientific Career: An Interview with Oliver Smithies
    Smithies O, Gitschier J.
    PLoS Genet. 2015 May; 11(5): e1005224. Published online 2015 May 28. doi: 10.1371/journal.pgen.1005224
    PMID: 26020970 PMCID: PMC4447374
  7. Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice.
    Hathaway CK, Gasim AM, Grant R, Chang AS, Kim HS, Madden VJ, Bagnell CR Jr, Jennette JC, Smithies O, Kakoki M.
    Proc Natl Acad Sci U S A. 2015 May 5;112(18):5815-20. doi: 10.1073/pnas.1504777112. Epub 2015 Apr 20.
    PMID: 25902541 PMCID: PMC4426439
  8. Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade.
    Hathaway CK, Grant R, Hagaman JR, Hiller S, Li F, Xu L, Chang AS, Madden VJ, Bagnell CR, Rojas M, Kim HS, Wu B, Zhou B, Smithies O, Kakoki M.
    Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5141-6. doi: 10.1073/pnas.1504557112. Epub 2015 Apr 6.
    PMID: 25848038 PMCID: PMC4413291
  9. Transforming growth factor beta1 and aldosterone.
    Matsuki K, Hathaway CK, Chang AS, Smithies O, Kakoki M.
    Curr Opin Nephrol Hypertens. 2015 Mar;24(2):139-44. doi: 10.1097/MNH.0000000000000100. Review.
    PMID:25587902 PMCID: PMC4838512
  10. The role of transforming growth factor β1 in the regulation of blood pressure.
    Matsuki K, Hathaway CK, Lawrence MG, Smithies O, Kakoki M.
    Curr Hypertens Rev. 2014;10(4):223-38. Review.
    PMID: 25801626 PMCID: PMC4842018
  11. Stable oligomeric clusters of gold nanoparticles: preparation, size distribution, derivatization, and physical and biological properties.
    Smithies O, Lawrence M, Testen A, Horne LP, Wilder J, Altenburg M, Bleasdale B, Maeda N, Koklic T.
    Langmuir. 2014 Nov 11;30(44):13394-404. doi: 10.1021/la5032637. Epub 2014 Oct 29.
    PMID: 25317930 PMCID: PMC4230385
  12. Colour blindness: still too many red-green figures.
    Allred SC, Schreiner WJ, Smithies O.
    Nature. 2014 Jun 19;510(7505):340. doi: 10.1038/510340e. No abstract available.
    PMID: 24943948
  13. The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension.
    Bai X, Lenhart KC, Bird KE, Suen AA, Rojas M, Kakoki M, Li F, Smithies O, Mack CP, Taylor JM.
    Nat Commun. 2013;4:2910. doi: 10.1038/ncomms3910.
    PMID: 24335996 PMCID: PMC4237314
  14.  Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
    Kakoki M, Pochynyuk OM, Hathaway CM, Tomita H, Hagaman JR, Kim HS, Zaika OL, Mamenko M, Kayashima Y, Matsuki K, Hiller S, Li F, Xu L, Grant R, Bertorello AM, Smithies O.
    Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5600-5. doi: 10.1073/pnas.1302641110. Epub 2013 Mar 15.
    PMID: 23503843 PMCID: PMC3619322
  15. Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression.
    Pandya K, Kohro T, Mimura I, Kobayashi M, Wada Y, Kodama T, Smithies O.
    Gene Expr. 2012;15(4):183-98.
    PMID: 22783727 PMCID: PMC3607203
  16. How it all began: a personal history of gel electrophoresis.
    Smithies O.
    Methods Mol Biol. 2012;869:1-21. doi: 10.1007/978-1-61779-821-4_1.
    PMID: 22585472
  17. Quantification of myocyte chemotaxis: a role for FAK in regulating directional motility.
    Zajac B, Hakim ZS, Cameron MV, Smithies O, Taylor JM.
    Methods Mol Biol. 2012;843:111-23. doi: 10.1007/978-1-61779-523-7_11.
    PMID: 22222526 PMCID: PMC4636020
  18. Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.
    Vashistha H, Singhal PC, Malhotra A, Husain M, Mathieson P, Saleem MA, Kuriakose C, Seshan S, Wilk A, Delvalle L, Peruzzi F, Giorgio M, Pelicci PG, Smithies O, Kim HS, Kakoki M, Reiss K, Meggs LG.
    Am J Physiol Renal Physiol. 2012 Dec 15;303(12):F1629-40. doi: 10.1152/ajprenal.00246.2012. Epub 2012 Sep 26.
    PMID:23019230 PMCID: PMC3532473
  19. eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype.
    Li F, Hagaman JR, Kim HS, Maeda N, Jennette JC, Faber JE, Karumanchi SA, Smithies O, Takahashi N.
    J Am Soc Nephrol. 2012 Apr;23(4):652-60. doi: 10.1681/ASN.2011040369. Epub 2012 Jan 26.
    PMID: 22282588 PMCID: PMC3312503
  20. The kallikrein-kinin system in diabetic nephropathy.
    Tomita H, Sanford RB, Smithies O, Kakoki M.
    Kidney Int. 2012 Apr;81(8):733-44. doi: 10.1038/ki.2011.499. Epub 2012 Feb 8. Review.
    PMID:22318421 PMCID: PMC3498986
  21. The kallikrein-kinin system and oxidative stress.
    Kayashima Y, Smithies O, Kakoki M.
    Curr Opin Nephrol Hypertens. 2012 Jan;21(1):92-6. doi: 10.1097/MNH.0b013e32834d54b1. Review.
    PMID:22048723 PMCID: PMC3657726
  22. Kallikrein-kinin system in diabetes in Kinins.     
    Kakoki M, Smithies O, Michael Bader, Ed., Max Delbruck Center for Molecular Medicine (MDC), Berlin-Buch, 2011, pp. 273-287.
  23. β-MyHC and cardiac hypertrophy: size does matter.
    Pandya K, Smithies O.
    Circ Res. 2011 Sep 2;109(6):609-10. doi: 10.1161/CIRCRESAHA.111.252619. No abstract available.
    PMID: 21885833
  24. Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
    Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N.
    Proc Natl Acad Sci U S A. 2011 May 24;108(21):8779-84. doi: 10.1073/pnas.1106344108. Epub 2011 May 9.
    PMID: 21555558 PMCID: PMC3102415
  25. Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells.
    Hatada S, Walton W, Hatada T, Wofford A, Fox R, Liu N, Lill MC, Fair JH, Kirby SL, Smithies O.
    Exp Hematol. 2011 Mar;39(3):375-83, 383.e1-4. doi: 10.1016/j.exphem.2010.12.007. Epub 2010 Dec 22.
    PMID: 21184801 PMCID: PMC3057214
  26. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy.
    Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N.
    Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2070-5. doi: 10.1073/pnas.1018766108. Epub 2011 Jan 18. Erratum in: Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3453.
    PMID: 21245338 PMCID: PMC3033253
  27.  Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression.
    Pandya K, Pulli B, Bultman S, Smithies O.
    Gene Expr. 2010;15(2):51-9.
    PMID: 21526716 PMCID: PMC3243912
  28. Genetically determined angiotensin converting enzyme level and myocardial tolerance to ischemia.
    Messadi E, Vincent MP, Griol-Charhbili V, Mandet C, Colucci J, Krege JH, Bruneval P, Bouby N,Smithies O, Alhenc-Gelas F, Richer C.
    FASEB J. 2010 Dec;24(12):4691-700. doi: 10.1096/fj.10-165902. Epub 2010 Jul 28.
    PMID: 20667972 PMCID: PMC3428376
  29. Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.
    Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE.
    Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18097-102. doi: 10.1073/pnas.1012826107. Epub 2010 Oct 5.
    PMID: 20923879 PMCID: PMC2964244
  30. Science brick by brick.
    Smithies O.
    Nature. 2010 Oct 14;467(7317):S6. doi: 10.1038/467S6a. No abstract available.
    PMID: 20944621
  31. Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice.
    Wende AR, Soto J, Olsen CD, Pires KM, Schell JC, Larrieu-Lahargue F, Litwin SE, Kakoki M, Takahashi N, Smithies O, Abel ED.
    Endocrinology. 2010 Aug;151(8):3536-42. doi: 10.1210/en.2010-0256. Epub 2010 May 25.
    PMID: 20501666 PMCID: PMC2940524
  32. Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
    Kakoki M, Sullivan KA, Backus C, Hayes JM, Oh SS, Hua K, Gasim AM, Tomita H, Grant R, Nossov SB, Kim HS, Jennette JC, Feldman EL, Smithies O.
    Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10190-5. doi: 10.1073/pnas.1005144107. Epub 2010 May 17.
    PMID: 20479236 PMCID: PMC2890475
  33. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990.
    Koller BH, Marrack P, Kappler JW, Smithies O.
    J Immunol. 2010 May 1;184(9):4592-5. No abstract available.
    PMID: 20410496
  34. Gender-dependent survival of allogeneic trophoblast stem cells in liver.
    Epple-Farmer J, Debeb BG, Smithies O, Binas B.
    Cell Transplant. 2009;18(7):769-76. doi: 10.3727/096368909X470856. Epub 2009 Apr 29.
    PMID: 19523327 PMCID: PMC3464099
  35.  Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.
    Scott NJ, Ellmers LJ, Lainchbury JG, Maeda N, Smithies O, Richards AM, Cameron VA.
    Biochim Biophys Acta. 2009 Dec;1792(12):1175-84. doi: 10.1016/j.bbadis.2009.09.009. Epub 2009 Sep 24.
    PMID: 19782130 PMCID: PMC2894466
  36. Mouse models of diabetic nephropathy.
    Brosius FC 3rd, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH, Levi M, McIndoe RA, Sharma K, Smithies O, Susztak K, Takahashi N, Takahashi T; Animal Models of Diabetic Complications Consortium.
    J Am Soc Nephrol. 2009 Dec;20(12):2503-12. doi: 10.1681/ASN.2009070721. Epub 2009 Sep 3. Review.
    PMID: 19729434 PMCID: PMC4075053
  37. Genetic variations in peroxisome proliferator-activated receptor gamma expression affect blood pressure.
    Tsai YS, Xu L, Smithies O, Maeda N.
    Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19084-9. doi: 10.1073/pnas.0909657106. Epub 2009 Nov 2.
    PMID: 19884495 PMCID: PMC2771745
  38.  Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.
    Huby AC, Rastaldi MP, Caron K, Smithies O, Dussaule JC, Chatziantoniou C.
    PLoS One. 2009 Aug 21;4(8):e6721. doi: 10.1371/journal.pone.0006721.
    PMID: 19696925 PMCID: PMC2725297
  39. Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain.
    Pandya K, Porter K, Rockman HA, Smithies O.
    Eur J Heart Fail. 2009 Jul;11(7):648-52. doi: 10.1093/eurjhf/hfp073.
    PMID: 19553396 PMCID: PMC2701279
  40. The kallikrein-kinin system in health and in diseases of the kidney.
    Kakoki M, Smithies O.
    Kidney Int. 2009 May;75(10):1019-30. doi: 10.1038/ki.2008.647. Epub 2009 Feb 4. Review.
    PMID: 19190676 PMCID: PMC3733452
  41. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice.
    Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R.
    Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1205-10. doi: 10.1073/pnas.0812436106. Epub 2009 Jan 21.
    PMID: 19164558 PMCID: PMC2633555
  42. Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
    Pandya K, Cowhig J, Brackhan J, Kim HS, Hagaman J, Rojas M, Carter CW Jr, Mao L, Rockman HA, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13063-8. doi: 10.1073/pnas.0805120105. Epub 2008 Aug 28.
    PMID: 18755891 PMCID: PMC2526551
  43. Tea with Dr Oliver Smithies, 2007 Nobel laureate in physiology and medicine. Interview by Dr. Anthony Viera.
    Smithies O.
    J Clin Hypertens (Greenwich). 2008 Aug;10(8):640-3. No abstract available.
    PMID: 18772647
  44. Turning pages (Nobel lecture).
    Smithies O.
    Chembiochem. 2008 Jun 16;9(9):1342-59. doi: 10.1002/cbic.200800205. No abstract available.
    PMID: 18543237
  45. Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.
    Brosnihan KB, Hodgin JB, Smithies O, Maeda N, Gallagher P.
    Exp Physiol. 2008 May;93(5):658-64. doi: 10.1113/expphysiol.2007.041806. Epub 2008 Jan 11.
    PMID: 18192335 PMCID: PMC2442755
  46. Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.
    Makhanova N, Hagaman J, Kim HS, Smithies O.
    Hypertension. 2008 Jan;51(1):134-40. Epub 2007 Nov 26.
    PMID: 18039983
  47. Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment.
    Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM.
    Mol Cell Biol. 2007 Aug;27(15):5352-64. Epub 2007 May 25.
    PMID: 17526730 PMCID: PMC1952084
  48. Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age.
    Dackor R, Fritz-Six K, Smithies O, Caron K.
    J Biol Chem. 2007 Jun 22;282(25):18094-9. Epub 2007 Apr 30.
    PMID: 17470425
  49. Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel.
    Yamaguchi N, Takahashi N, Xu L, Smithies O, Meissner G.
    J Clin Invest. 2007 May;117(5):1344-53. Epub 2007 Apr 12.
    PMID: 17431507 PMCID: PMC1847534
  50. Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury.
    Kakoki M, McGarrah RW, Kim HS, Smithies O.
    Proc Natl Acad Sci U S A. 2007 May 1;104(18):7576-81. Epub 2007 Apr 23.
    PMID: 17452647 PMCID: PMC1855073
  51. Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis.
    Ellmers LJ, Scott NJ, Piuhola J, Maeda N, Smithies O, Frampton CM, Richards AM, Cameron VA.
    J Mol Endocrinol. 2007 Feb;38(1-2):245-57.
    PMID: 17293444
  52. Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males.
    Caron K, Hagaman J, Nishikimi T, Kim HS, Smithies O.
    Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3420-5. Epub 2007 Feb 20.
    PMID:17360661 PMCID: PMC1802008
  53. Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.
    Makhanova N, Sequeira-Lopez ML, Gomez RA, Kim HS, Smithies O.
    Hypertension. 2006 Dec;48(6):1151-9. Epub 2006 Oct 30.
    PMID: 17075030
  54. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
    Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH, Coffman TM.
    Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17985-90. Epub 2006 Nov 7.
    PMID: 17090678 PMCID: PMC1693859
  55. Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo.
    Pandya K, Kim HS, Smithies O.
    Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16864-9. Epub 2006 Oct 26.
    PMID: 17068123 PMCID: PMC1624863
  56. Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice.
    Li M, Yee D, Magnuson TR, Smithies O, Caron KM.
    J Clin Invest. 2006 Oct;116(10):2653-62. Epub 2006 Sep 14.
    PMID:16981008 PMCID: PMC1564429
  57. Amino acids as modulators of endothelium-derived nitric oxide.
    Kakoki M, Kim HS, Edgell CJ, Maeda N, Smithies O, Mattson DL.
    Am J Physiol Renal Physiol. 2006 Aug;291(2):F297-304. Epub 2006 Mar 28.
    PMID: 16571593
  58. Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis.
    Yasuda O, Fukuo K, Sun X, Nishitani M, Yotsui T, Higuchi M, Suzuki T, Rakugi H, Smithies O, Maeda N, Ogihara T.
    J Biol Chem. 2006 Aug 18;281(33):23899-907. Epub 2006 Jun 16.
    PMID: 16782708
  59. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.
    Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA.
    J Clin Invest. 2006 Jun;116(6):1547-60.
    PMID: 16741575 PMCID: PMC1464895
  60. A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation.
    Ciavatta D, Kalantry S, Magnuson T, Smithies O.
    Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9958-63. Epub 2006 Jun 15.
    PMID: 16777957 PMCID: PMC1479543
  61. Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors.
    Kakoki M, Kizer CM, Yi X, Takahashi N, Kim HS, Bagnell CR, Edgell CJ, Maeda N, Jennette JC,Smithies O.
    J Clin Invest. 2006 May;116(5):1302-9. Epub 2006 Apr 6.
    PMID: 16604193 PMCID: PMC1430357
  62. Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene.
    Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM.
    Mol Cell Biol. 2006 Apr;26(7):2511-8.
    PMID: 16537897 PMCID: PMC1430335
  63. Kidney function in mice lacking aldosterone.
    Makhanova N, Lee G, Takahashi N, Sequeira Lopez ML, Gomez RA, Kim HS, Smithies O.
    Am J Physiol Renal Physiol. 2006 Jan;290(1):F61-9. Epub 2005 Aug 23.
    PMID: 16118390
  64. Isolating gene-corrected stem cells without drug selection.
    Hatada S, Arnold LW, Hatada T, Cowhig JE Jr, Ciavatta D, Smithies O.
    Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16357-61. Epub 2005 Oct 28.
    PMID: 16258059 PMCID: PMC1274242
  65. An improved technique for tail-cuff blood pressure measurements with dark-tailed mice.
    Hagaman JR, John S, Xu L, Smithies O, Maeda N.
    Contemp Top Lab Anim Sci. 2005 Sep;44(5):43-6.
    PMID: 16138782
  66. Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.
    Lee G, Makhanova N, Caron K, Lopez ML, Gomez RA, Smithies O, Kim HS.
    Endocrinology. 2005 Jun;146(6):2650-6. Epub 2005 Feb 24.
    PMID: 15731365
  67. An interview with… Oliver Smithies [interviewed by Magdalena Skipper].
    Smithies O.
    Nat Rev Genet. 2005 May;6(5):350. No abstract available.
    PMID: 15880879
  68. Many little things: one geneticist’s view of complex diseases.
    Smithies O.
    Nat Rev Genet. 2005 May;6(5):419-25. Review.
    PMID: 15861211
  69. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system.
    Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, Spurney RF, Kim HS,Smithies O, Le TH, Coffman TM.
    J Clin Invest. 2005 Apr;115(4):1092-9.
    PMID: 15841186 PMCID: PMC1070417
  70. Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene.
    Nishikimi T, Hagaman JR, Takahashi N, Kim HS, Matsuoka H, Smithies O, Maeda N.
    Cardiovasc Res. 2005 Apr 1;66(1):94-103. Epub 2005 Jan 15.
    PMID: 15769452
  71. Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro.
    Fair JH, Cairns BA, Lapaglia MA, Caballero M, Pleasant WA, Hatada S, Kim HS, Gui T, Pevny L, Meyer AA, Stafford DW, Smithies O, Frelinger JA.
    Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2958-63. Epub 2005 Feb 7.
    PMID: 15699326 PMCID: PMC548326
  72. Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type.
    Takahashi N, Lopez ML, Cowhig JE Jr, Taylor MA, Hatada T, Riggs E, Lee G, Gomez RA, Kim HS,Smithies O.
    J Am Soc Nephrol. 2005 Jan;16(1):125-32. Epub 2004 Nov 24.
    PMID: 15563565
  73. Lifelong genetic minipumps.
    Caron KM, James LR, Lee G, Kim HS, Smithies O.
    Physiol Genomics. 2005 Jan 20;20(2):203-9. Epub 2004 Dec 7.
    PMID: 15585607
  74. Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences.
    Cohen SM, Hatada S, Brylawski BP, Smithies O, Kaufman DG, Cordeiro-Stone M.
    Genomics. 2004 Sep;84(3):475-84.
    PMID: 15498455
  75. Three-dimensional diffusion tensor microscopy of fixed mouse hearts.
    Jiang Y, Pandya K, Smithies O, Hsu EW.
    Magn Reson Med. 2004 Sep;52(3):453-60.
    PMID: 15334561
  76. Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor.
    Kakoki M, Takahashi N, Jennette JC, Smithies O.
    Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13302-5. Epub 2004 Aug 23.
    PMID: 15326315 PMCID: PMC516527
  77. A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice.
    Le TH, Oliverio MI, Kim HS, Salzler H, Dash RC, Howell DN, Smithies O, Bronson S, Coffman TM.
    Physiol Genomics. 2004 Aug 11;18(3):290-8.
    PMID: 15306694
  78. E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
    Goulet JL, Pace AJ, Key ML, Byrum RS, Nguyen M, Tilley SL, Morham SG, Langenbach R, Stock JL, McNeish JD, Smithies O, Coffman TM, Koller BH.
    J Immunol. 2004 Jul 15;173(2):1321-6.
    PMID: 15240726
  79. Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened.
    Sequeira López ML, Pentz ES, Nomasa T, Smithies O, Gomez RA.
    Dev Cell. 2004 May;6(5):719-28.
    PMID: 15130496
  80. Altering the expression in mice of genes by modifying their 3′ regions.
    Kakoki M, Tsai YS, Kim HS, Hatada S, Ciavatta DJ, Takahashi N, Arnold LW, Maeda N, Smithies O.
    Dev Cell. 2004 Apr;6(4):597-606.
    PMID: 15068798
  81. Human genetics, animal models and computer simulations for studying hypertension.
    Takahashi N, Smithies O.
    Trends Genet. 2004 Mar;20(3):136-45. Review.
    PMID: 15036807
  82. Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene.
    Caron KM, James LR, Kim HS, Knowles J, Uhlir R, Mao L, Hagaman JR, Cascio W, Rockman H,Smithies O.
    Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3106-11. Epub 2004 Feb 20.
    PMID: 14978280 PMCID: PMC365751
  83. Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion.
    Shi SJ, Vellaichamy E, Chin SY, Smithies O, Navar LG, Pandey KN.
    Am J Physiol Renal Physiol. 2003 Oct;285(4):F694-702. Epub 2003 Jun 24.
    PMID: 12824076
  84. Physiological impact of increased expression of the AT1 angiotensin receptor.
    Le TH, Kim HS, Allen AM, Spurney RF, Smithies O, Coffman TM.
    Hypertension. 2003 Oct;42(4):507-14. Epub 2003 Sep 8.
    PMID: 12963678
  85. Genetic contributions to generalized arousal of brain and behavior.
    Garey J, Goodwillie A, Frohlich J, Morgan M, Gustafsson JA, Smithies O, Korach KS, Ogawa S, Pfaff DW.
    Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11019-22. Epub 2003 Aug 20.
    PMID: 12930901 PMCID: PMC196919
  86. Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm.
    Fair JH, Cairns BA, Lapaglia M, Wang J, Meyer AA, Kim H, Hatada S, Smithies O, Pevny L.
    Surgery. 2003 Aug;134(2):189-96.
    PMID: 12947317
  87. Minireview: computer simulations of blood pressure regulation by the renin-angiotensin system.
    Takahashi N, Hagaman JR, Kim HS, Smithies O.
    Endocrinology. 2003 Jun;144(6):2184-90. Review.
    PMID: 12746272
  88. Why the kidney glomerulus does not clog: a gel permeation/diffusion hypothesis of renal function.
    Smithies O.
    Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4108-13. Epub 2003 Mar 24.
    PMID: 12655073 PMCID: PMC153056
  89. Estrogen-induced osteogenesis in intact female mice lacking ERbeta.
    McDougall KE, Perry MJ, Gibson RL, Bright JM, Colley SM, Hodgin JB, Smithies O, Tobias JH.
    Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E817-23.
    PMID: 12217900
  90. Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis.
    Ellmers LJ, Knowles JW, Kim HS, Smithies O, Maeda N, Cameron VA.
    Am J Physiol Heart Circ Physiol. 2002 Aug;283(2):H707-14.
    PMID: 12124219 PMCID: PMC4321891
  91. Targeted disruption of hsp70.1 sensitizes to osmotic stress.
    Shim EH, Kim JI, Bang ES, Heo JS, Lee JS, Kim EY, Lee JE, Park WY, Kim SH, Kim HS, Smithies O, Jang JJ, Jin DI, Seo JS.
    EMBO Rep. 2002 Sep;3(9):857-61. Epub 2002 Aug 16.
    PMID: 12189176 PMCID: PMC1084228
  92. A genetically clamped renin transgene for the induction of hypertension.
    Caron KM, James LR, Kim HS, Morham SG, Sequeira Lopez ML, Gomez RA, Reudelhuber TL,Smithies O.
    Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8248-52. Epub 2002 May 28.
    PMID: 12034874 PMCID: PMC123053
  93. Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice.
    Nomura M, Durbak L, Chan J, Smithies O, Gustafsson JA, Korach KS, Pfaff DW, Ogawa S.
    Horm Behav. 2002 May;41(3):288-96.
    PMID: 11971662
  94. Impaired T cell function in RANTES-deficient mice.
    Makino Y, Cook DN, Smithies O, Hwang OY, Neilson EG, Turka LA, Sato H, Wells AD, Danoff TM.
    Clin Immunol. 2002 Mar;102(3):302-9.
    PMID: 11890717
  95. Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene.
    Takahashi N, Brooks HL, Wade JB, Liu W, Kondo Y, Ito S, Knepper MA, Smithies O.
    J Am Soc Nephrol. 2002 Mar;13(3):604-10.
    PMID: 11856763
  96. Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration.
    Kim HS, Lee G, John SW, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4602-7. Epub 2002 Mar 19.
    PMID: 11904385 PMCID: PMC123694
  97. Multiple roles of adrenomedullin revealed by animal models.
    Caron KM, Smithies O.
    Microsc Res Tech. 2002 Apr 1;57(1):55-9. Review.
    PMID: 11921356
  98. Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice.
    Hodgin JB, Knowles JW, Kim HS, Smithies O, Maeda N.
    J Clin Invest. 2002 Feb;109(4):541-8.
    PMID: 11854327 PMCID: PMC150875
  99. Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy.
    Klinger JR, Warburton RR, Pietras L, Oliver P, Fox J, Smithies O, Hill NS.
    Am J Physiol Heart Circ Physiol. 2002 Jan;282(1):H58-65.
    PMID: 11748047
  100. Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta.
    Zhu Y, Bian Z, Lu P, Karas RH, Bao L, Cox D, Hodgin J, Shaul PW, Thoren P, Smithies O, Gustafsson JA, Mendelsohn ME.
    Science. 2002 Jan 18;295(5554):505-8.
    PMID: 11799247
  101.  Albuminuria in mice after injection of antibodies against aminopeptidase A: role of angiotensin II.
    Gerlofs-Nijland ME, Assmann KJ, Dijkman HB, Dieker JW, van Son JP, Mentzel S, van Kats JP, Danser AH, Smithies O, Groenen PJ, Wetzels JF.
    J Am Soc Nephrol. 2001 Dec;12(12):2711-20.
    PMID: 11729240
  102. Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition.
    Athirakul K, Kim HS, Audoly LP, Smithies O, Coffman TM.
    Kidney Int. 2001 Dec;60(6):2324-9.
    PMID: 11737606
  103. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse.
    Huang W, Gallois Y, Bouby N, Bruneval P, Heudes D, Belair MF, Krege JH, Meneton P, Marre M,Smithies O, Alhenc-Gelas F.
    Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13330-4. Epub 2001 Oct 30.
    PMID: 11687636 PMCID: PMC60870
  104. Forty years with homologous recombination.
    Smithies O.
    Nat Med. 2001 Oct;7(10):1083-6. No abstract available.
    PMID: 11590419
  105. Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus.
    Gilmore RC, Baker J Jr, Dempsey S, Marchan R, Corprew RN Jr, Byrd G, Maeda N, Smithies O, Bukoski RD, Harewood KR, Chatterjee PK.
    Gene. 2001 Sep 5;275(1):65-72.
    PMID: 11574153
  106. Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide.
    Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N.
    Biochem J. 2001 Sep 1;358(Pt 2):379-87.
    PMID: 11513736 PMCID: PMC1222070
  107. Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d.
    Pentz ES, Lopez ML, Kim HS, Carretero O, Smithies O, Gomez RA.
    Physiol Genomics. 2001 Jun 6;6(1):45-55.
    PMID: 11395546
  108. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.
    Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N.
    J Clin Invest. 2001 Apr;107(8):975-84.
    PMID: 11306601 PMCID:PMC199554
  109. Estrogen receptor alpha is a major mediator of 17beta-estradiol’s atheroprotective effects on lesion size in Apoe-/- mice.
    Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N.
    J Clin Invest. 2001 Feb;107(3):333-40.
    PMID: 11160157 PMCID: PMC199197
  110. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.
    Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R.
    Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1059-64. Epub 2001 Jan 23.
    PMID: 11158594 PMCID: PMC14708
  111. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene.
    Caron KM, Smithies O.
    Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):615-9. Epub 2001 Jan 9.
    PMID: 11149956 PMCID: PMC14636
  112. Studying the Genetics of Complex but Common Human Diseases Using Mice    
    Maeda N, and Smithies O.
    in Biology of Menopause, ed. F. L. Bellino, Springer-Verlag, 2000; New York, NY, pp. 238-246.
  113. Importance of quantitative genetic variations in the etiology of hypertension.
    Smithies O, Kim HS, Takahashi N, Edgell MH.
    Kidney Int. 2000 Dec;58(6):2265-80. Review.
    PMID: 11115061
  114. Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice.
    Norwood VF, Morham SG, Smithies O.
    Kidney Int. 2000 Dec;58(6):2291-300.
    PMID: 11115063
  115. Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO).
    Ogawa S, Chester AE, Hewitt SC, Walker VR, Gustafsson JA, Smithies O, Korach KS, Pfaff DW.
    Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14737-41.
    PMID: 11114183 PMCID: PMC18988
  116. Gene correction in hematopoietic progenitor cells by homologous recombination.
    Hatada S, Nikkuni K, Bentley SA, Kirby S, Smithies O.
    Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13807-11.
    PMID: 11087825 PMCID: PMC17657
  117. Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.
    Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG,Smithies O, Langenbach R.
    Cancer Res. 2000 Sep 1;60(17):4705-8.
    PMID: 10987272
  118. Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation.
    Kirby S, Walton W, Smithies O.
    Blood. 2000 Jun 15;95(12):3710-5.
    PMID: 10845901
  119. Uncompensated polyuria in a mouse model of Bartter’s syndrome.
    Takahashi N, Chernavvsky DR, Gomez RA, Igarashi P, Gitelman HJ, Smithies O.
    Proc Natl Acad Sci U S A. 2000 May 9;97(10):5434-9.
    PMID: 10779555 PMCID: PMC25846
  120. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment.
    Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N.
    J Clin Invest. 2000 Feb;105(4):451-8.
    PMID: 10683374 PMCID: PMC289160
  121. Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.
    Morteau O, Morham SG, Sellon R, Dieleman LA, Langenbach R, Smithies O, Sartor RB.
    J Clin Invest. 2000 Feb;105(4):469-78.
    PMID: 10683376 PMCID: PMC289156
  122. Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
    Oliverio MI, Best CF, Smithies O, Coffman TM.
    Hypertension. 2000 Feb;35(2):550-4.
    PMID: 10679496
  123. Abnormal water metabolism in mice lacking the type 1A receptor for ANG II.
    Oliverio MI, Delnomdedieu M, Best CF, Li P, Morris M, Callahan MF, Johnson GA, Smithies O, Coffman TM.
    Am J Physiol Renal Physiol. 2000 Jan;278(1):F75-82.
    PMID: 10644657
  124. Quantitative genetic variations and essential hypertension.
    Smithies O.
    Harvey Lect. 1999-2000;95:1-20. No abstract available.
    PMID: 11446106
  125. Alexander George Ogston: 30 January 1911-29 June 1996.
    Smithies O.
    Biogr Mem Fellows R Soc. 1999;45:351-64. No abstract available.
    PMID: 11624284
  126. Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.
    Nataraj C, Oliverio MI, Mannon RB, Mannon PJ, Audoly LP, Amuchastegui CS, Ruiz P, Smithies O, Coffman TM.
    J Clin Invest. 1999 Dec;104(12):1693-701.
    PMID: 10606623 PMCID: PMC409880
  127. Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.
    Karas RH, Hodgin JB, Kwoun M, Krege JH, Aronovitz M, Mackey W, Gustafsson JA, Korach KS,Smithies O, Mendelsohn ME.
    Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15133-6.
    PMID: 10611350 PMCID: PMC24785
  128.  Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models.
    Pandey KN, Oliver PM, Maeda N, Smithies O.
    Endocrinology. 1999 Nov;140(11):5112-9.
    PMID: 10537139
  129. Gene targeting approaches to analyzing hypertension.
    Takahashi N, Smithies O.
    J Am Soc Nephrol. 1999 Jul;10(7):1598-605. Review.
    PMID: 10405217
  130. The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.
    Matsukawa N, Grzesik WJ, Takahashi N, Pandey KN, Pang S, Yamauchi M, Smithies O.
    Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7403-8.
    PMID: 10377427 PMCID: PMC22098
  131. Genetic disruption of atrial natriuretic peptide causes pulmonary hypertension in normoxic and hypoxic mice.
    Klinger JR, Warburton RR, Pietras LA, Smithies O, Swift R, Hill NS.
    Am J Physiol. 1999 May;276(5 Pt 1):L868-74.
    PMID: 10330043
  132. Tubuloglomerular feedback in ACE-deficient mice.
    Traynor T, Yang T, Huang YG, Krege JH, Briggs JP, Smithies O, Schnermann J.
    Am J Physiol. 1999 May;276(5 Pt 2):F751-7.
    PMID: 10330057
  133. Homeostasis in mice with genetically decreased angiotensinogen is primarily by an increased number of renin-producing cells.
    Kim HS, Maeda N, Oh GT, Fernandez LG, Gomez RA, Smithies O.
    J Biol Chem. 1999 May 14;274(20):14210-7.
    PMID: 10318840
  134. CD8+ T cells are a biologically relevant source of macrophage inflammatory protein-1 alpha in vivo.
    Cook DN, Smithies O, Strieter RM, Frelinger JA, Serody JS.
    J Immunol. 1999 May 1;162(9):5423-8.
    PMID: 10228020
  135. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice.
    Fern RJ, Yesko CM, Thornhill BA, Kim HS, Smithies O, Chevalier RL.
    J Clin Invest. 1999 Jan;103(1):39-46.
    PMID: 9884332 PMCID: PMC407859
  136. The influence of chromosomal location on the expression of two transgenes in mice.
    Hatada S, Kuziel W, Smithies O, Maeda N.
    J Biol Chem. 1999 Jan 8;274(2):948-55.
    PMID: 9873036
  137. Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
    Krege JH, Hodgin JB, Couse JF, Enmark E, Warner M, Mahler JF, Sar M, Korach KS, Gustafsson JA, Smithies O.
    Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15677-82.
    PMID: 9861029 PMCID: PMC28103
  138. Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
    Oliverio MI, Kim HS, Ito M, Le T, Audoly L, Best CF, Hiller S, Kluckman K, Maeda N, Smithies O, Coffman TM.
    Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15496-501.
    PMID: 9860997 PMCID: PMC28071
  139. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
    Thomas DW, Mannon RB, Mannon PJ, Latour A, Oliver JA, Hoffman M, Smithies O, Koller BH, Coffman TM.
    J Clin Invest. 1998 Dec 1;102(11):1994-2001.
    PMID: 9835625 PMCID: PMC509152
  140. Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
    Thresher RJ, Vitaterna MH, Miyamoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L,Smithies O, Takahashi JS, Sancar A.
    Science. 1998 Nov 20;282(5393):1490-4.
    PMID: 9822380
  141. Absence of macrophage inflammatory protein-1alpha prevents the development of blinding herpes stromal keratitis.
    Tumpey TM, Cheng H, Cook DN, Smithies O, Oakes JE, Lausch RN.
    J Virol. 1998 May;72(5):3705-10.
    PMID: 9557652 PMCID: PMC109592
  142. A common human beta globin splicing mutation modeled in mice.
    Lewis J, Yang B, Kim R, Sierakowska H, Kole R, Smithies O, Maeda N.
    Blood. 1998 Mar 15;91(6):2152-6.
    PMID: 9490703
  143. Angiotensin-converting enzyme and male fertility.
    Hagaman JR, Moyer JS, Bachman ES, Sibony M, Magyar PL, Welch JE, Smithies O, Krege JH, O’Brien DA.
    Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2552-7.
    PMID: 9482924 PMCID: PMC19410
  144. Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner.
    Oliver PM, John SW, Purdy KE, Kim R, Maeda N, Goy MF, Smithies O.
    Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2547-51.
    PMID: 9482923 PMCID: PMC19408
  145. Rapid genotyping of mice with hemoglobinopathies and globin transgenes.
    Whitney JB 3rd, Leder A, Lewis J, Popp RA, Paszty C, Rubin EM, Shehee WR, Townes TM,Smithies O.
    Biochem Genet. 1998 Feb;36(1-2):65-77.
    PMID: 9562907
  146. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
    Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC.
    J Clin Invest. 1998 Feb 15;101(4):731-6.
    PMID: 9466966 PMCID: PMC508619
  147. Renal growth and development in mice lacking AT1A receptors for angiotensin II.
    Oliverio MI, Madsen K, Best CF, Ito M, Maeda N, Smithies O, Coffman TM.
    Am J Physiol. 1998 Jan;274(1 Pt 2):F43-50.
    PMID: 9458822
  148. Characterization of prostaglandin H synthase 2 deficient mice and implications for mechanisms of NSAID action.
    Morham SG, Langenbach R, Mahler J, Smithies O.
    Adv Exp Med Biol. 1997;407:131-8. No abstract available.
    PMID: 9321943
    UNC Health Sciences Library owns print.
  149. Theodore Cooper Memorial Lecture. A mouse view of hypertension.
    Smithies O.
    Hypertension. 1997 Dec;30(6):1318-24. Review.
    PMID: 9403547
  150. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A.
    Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N.
    Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14730-5.
    PMID: 9405681 PMCID: PMC25105
  151. A coagulation factor IX-deficient mouse model for human hemophilia B.
    Lin HF, Maeda N, Smithies O, Straight DL, Stafford DW.
    Blood. 1997 Nov 15;90(10):3962-6.
    PMID: 9354664
  152. Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15.
    Savinova OV, Matsukawa N, Smithies O, John SW.
    Mamm Genome. 1997 Oct;8(10):788. No abstract available.
    PMID: 9321481
  153. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.
    Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N.
    Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12053-8.
    PMID: 9342361 PMCID: PMC23699
  154.  Angiotensin-converting enzyme gene and atherosclerosis.
    Krege JH, Moyer JS, Langenbach LL, Peng L, Zhang SH, Maeda N, Reddick RL, Smithies O.
    Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1245-50.
    PMID: 9261253
  155. Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.
    Tian B, Meng QC, Chen YF, Krege JH, Smithies O, Oparil S.
    Hypertension. 1997 Jul;30(1 Pt 1):128-33.
    PMID: 9231832
  156. Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
    Tsuda H, Maynard-Currie CE, Reid LH, Yoshida T, Edamura K, Maeda N, Smithies O, Jakobovits A.
    Genomics. 1997 Jun 15;42(3):413-21.
    PMID: 9205113
  157. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation.
    Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM.
    Am J Physiol. 1997 Apr;272(4 Pt 2):F515-20.
    PMID: 9140053
  158. Mouse angiotensin receptor genes Agtr1a and Agtr1b map to chromosomes 13 and 3.
    MacTaggart TE, Ito M, Smithies O, John SW.
    Mamm Genome. 1997 Apr;8(4):294-5. No abstract available.
    PMID: 9096120
  159. Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
    Davisson RL, Kim HS, Krege JH, Lager DJ, Smithies O, Sigmund CD.
    J Clin Invest. 1997 Mar 15;99(6):1258-64.
    PMID: 9077534 PMCID: PMC507940
  160. Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme.
    Hilgers KF, Reddi V, Krege JH, Smithies O, Gomez RA.
    Hypertension. 1997 Jan;29(1 Pt 2):216-21.
    PMID: 9039105
  161. Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis.
    Krege JH, Kim HS, Moyer JS, Jennette JC, Peng L, Hiller SK, Smithies O.
    Hypertension. 1997 Jan;29(1 Pt 2):150-7.
    PMID: 9039095
  162. Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.
    Morham SG, Kluckman KD, Voulomanos N, Smithies O.
    Mol Cell Biol. 1996 Dec;16(12):6804-9.
    PMID: 8943335 PMCID: PMC231683
  163. Elevated blood pressures in mice lacking endothelial nitric oxide synthase.
    Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VE, Sherman PA, Sessa WC,Smithies O.
    Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13176-81.
    PMID: 8917564 PMCID: PMC24066
  164. Two distinct apolipoprotein B alleles in mice generated by a single ‘in-out’ targeting.
    Toth LR, Smith TJ, Jones C, de Silva HV, Smithies O, Maeda N.
    Gene. 1996 Oct 31;178(1-2):161-8.
    PMID: 8921909
  165. Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
    Bozza PT, Payne JL, Morham SG, Langenbach R, Smithies O, Weller PF.
    Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11091-6.
    PMID: 8855314 PMCID: PMC38289
  166. Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
    Kirby SL, Cook DN, Walton W, Smithies O.
    Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9402-7.
    PMID: 8790342 PMCID: PMC38440
  167. Single-copy transgenic mice with chosen-site integration.
    Bronson SK, Plaehn EG, Kluckman KD, Hagaman JR, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9067-72.
    PMID: 8799155 PMCID: PMC38596
  168. Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP.
    John SW, Veress AT, Honrath U, Chong CK, Peng L, Smithies O, Sonnenberg H.
    Am J Physiol. 1996 Jul;271(1 Pt 2):R109-14.
    PMID: 8760210
  169. Gene modification via “plug and socket” gene targeting.
    Lewis J, Yang B, Detloff P, Smithies O.
    J Clin Invest. 1996 Jan 1;97(1):3-5. Review. No abstract available.
    PMID: 8550847 PMCID: PMC507055
  170. Using animal models to dissect complex traits.
    Krege JH, Kurtz TW, Smithies, O
    In Mockrin S.C., ed. Molecular Genetics and Gene Therapy of Cardiovascular Diseases.
    New York: Marcel Dekker, Inc., (1995).
  171. A mouse model for beta 0-thalassemia.
    Yang B, Kirby S, Lewis J, Detloff PJ, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11608-12.
    PMID: 8524813 PMCID: PMC40451
  172. Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.
    Couse JF, Curtis SW, Washburn TF, Lindzey J, Golding TS, Lubahn DB, Smithies O, Korach KS.
    Mol Endocrinol. 1995 Nov;9(11):1441-54.
    PMID: 8584021
  173. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
    Laubach VE, Shesely EG, Smithies O, Sherman PA.
    Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10688-92.
    PMID: 7479866 PMCID: PMC40677
  174. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.
    Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Lee CA, Goulding EH, Kluckman KD, Kim HS, Smithies O.
    Cell. 1995 Nov 3;83(3):483-92.
    PMID: 8521478
  175. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.
    Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O.
    Cell. 1995 Nov 3;83(3):473-82.
    PMID: 8521477
  176. Requirement of MIP-1 alpha for an inflammatory response to viral infection.
    Cook DN, Beck MA, Coffman TM, Kirby SL, Sheridan JF, Pragnell IB, Smithies O.
    Science. 1995 Sep 15;269(5230):1583-5.
    PMID: 7667639
  177. Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
    Smithies O, Maeda N.
    Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5266-72. Review.
    PMID: 7777495 PMCID: PMC41675
  178. A noninvasive computerized tail-cuff system for measuring blood pressure in mice.
    Krege JH, Hodgin JB, Hagaman JR, Smithies O.
    Hypertension. 1995 May;25(5):1111-5.
    PMID: 7737724
  179. Male-female differences in fertility and blood pressure in ACE-deficient mice.
    Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O’Brien DA, Smithies O.
    Nature. 1995 May 11;375(6527):146-8.
    PMID: 7753170
  180. High incidence of XXY and XYY males among the offspring of female chimeras from embryonic stem cells.
    Bronson SK, Smithies O, Mascarello JT.
    Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3120-3.
    PMID: 7724525 PMCID: PMC42116
  181. Regulation of blood pressure by the type 1A angiotensin II receptor gene.
    Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM.
    Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3521-5.
    PMID: 7724593 PMCID: PMC42199
  182. Genetic control of blood pressure and the angiotensinogen locus.
    Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2735-9.
    PMID: 7708716 PMCID: PMC42293
  183. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension.
    John SW, Krege JH, Oliver PM, Hagaman JR, Hodgin JB, Pang SC, Flynn TG, Smithies O.
    Science. 1995 Feb 3;267(5198):679-81. Erratum in: Science 1995 Mar 24;267(5205):1753.
    PMID: 7839143
  184. Early days of gel electrophoresis.
    Smithies O.
    Genetics. 1995 Jan;139(1):1-4. No abstract available.
    PMID: 7705616 PMCID: PMC1206310
  185. Altering mice by homologous recombination using embryonic stem cells.
    Bronson SK, Smithies O.
    J Biol Chem. 1994 Nov 4;269(44):27155-8. Review. No abstract available.
    PMID: 7961620
  186. Deletion and replacement of the mouse adult beta-globin genes by a “plug and socket” repeated targeting strategy.
    Detloff PJ, Lewis J, John SW, Shehee WR, Langenbach R, Maeda N, Smithies O.
    Mol Cell Biol. 1994 Oct;14(10):6936-43.
    PMID: 7935410 PMCID: PMC359224
  187. Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.
    Smithies O, Kim HS.
    Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3612-5.
    PMID: 8170956 PMCID: PMC43630
  188. The structure and evolution of the human salivary proline-rich protein gene family.
    Kim HS, Lyons KM, Saitoh E, Azen EA, Smithies O, Maeda N.
    Mamm Genome. 1993;4(1):3-14.
    PMID: 8422499
  189. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
    Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O.
    Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11162-6.
    PMID: 8248223 PMCID: PMC47942
  190. Improved renal function in mouse kidney allografts lacking MHC class I antigens.
    Coffman T, Geier S, Ibrahim S, Griffiths R, Spurney R, Smithies O, Koller B, Sanfilippo F.
    J Immunol. 1993 Jul 1;151(1):425-35.
    PMID: 8326135
  191. Animal models of human genetic diseases.
    Smithies O.
    Trends Genet. 1993 Apr;9(4):112-6. Review.
    PMID: 8516844
  192. Islet allograft, islet xenograft, and skin allograft survival in CD8+ T lymphocyte-deficient mice.
    Desai NM, Bassiri H, Kim J, Koller BH, Smithies O, Barker CF, Naji A, Markmann JF.
    Transplantation. 1993 Apr;55(4):718-22.
    PMID: 8475541
  193. TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice.
    Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, Lee DC.
    Cell. 1993 Apr 23;73(2):263-78.
    PMID: 8477445
  194. Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene.
    Shehee WR, Oliver P, Smithies O.
    Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3177-81.
    PMID: 8475058 PMCID: PMC46262
  195. Pancreatic islet allograft and xenograft survival in CD8+ T-lymphocyte-deficient recipients.
    Desai NM, Bassiri H, Odorico JS, Koller BH, Smithies O, Naji A, Barker CF, Markmann JF.
    Transplant Proc. 1993 Feb;25(1 Pt 2):961-2. No abstract available.
    PMID: 8442280
  196. Altering genes in animals by gene targeting.
    Koller BH, Smithies O.
    Annu Rev Immunol. 1992;10:705-30. Review.
    PMID: 1591000
  197. “Gene Targeting and Electroporation”
    Reid LH, Smithies O. 
    in Guide to Electroporation and Electrofusion Academic Press, Inc. (1992).
  198. Indefinite survival of MHC class I-deficient murine pancreatic islet allografts.
    Markmann JF, Bassiri H, Desai NM, Odorico JS, Kim JI, Koller BH, Smithies O, Barker CF.
    Transplantation. 1992 Dec;54(6):1085-9.
    PMID: 1465773
  199.  An animal model for cystic fibrosis made by gene targeting.
    Snouwaert JN, Brigman KK, Latour AM, Malouf NN, Boucher RC, Smithies O, Koller BH.
    Science. 1992 Aug 21;257(5073):1083-8.
    PMID: 1380723
  200. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis.
    Clarke LL, Grubb BR, Gabriel SE, Smithies O, Koller BH, Boucher RC.
    Science. 1992 Aug 21;257(5073):1125-8.
    PMID: 1380724
  201. Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses.
    Spriggs MK, Koller BH, Sato T, Morrissey PJ, Fanslow WC, Smithies O, Voice RF, Widmer MB, Maliszewski CR.
    Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6070-4.
    PMID: 1631092 PMCID: PMC49439
  202. “Altering Genes in Animals and Humans.”
    Smithies O.
    Etiology of Human Disease at the DNA Level. Raven Press, Ltd. New York, NY 1991.
  203. Correction of the Human Sickle Cell Gene Using Targeted Gene Replacement.
    Popovich BW, Kim HS, Shesely EG, Shehee WR, Papayannopoulou T, Smithies O.
    in The Regulation of Hemoglobin Switching editors G. Stamatoyannopoulos and A.W. Nienhuis.
    pp:526 540 (1991).
  204. A dominant positive and negative selectable gene for use in mammalian cells.
    Schwartz F, Maeda N, Smithies O, Hickey R, Edelmann W, Skoultchi A, Kucherlapati R.
    Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10416-20.
    PMID: 1720540 PMCID: PMC52939
  205. Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells.
    Koller BH, Kim HS, Latour AM, Brigman K, Boucher RC Jr, Scambler P, Wainwright B, Smithies O.
    Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10730-4.
    PMID: 1720548 PMCID: PMC53004
  206. Double-strand gap repair in a mammalian gene targeting reaction.
    Valancius V, Smithies O.
    Mol Cell Biol. 1991 Sep;11(9):4389-97.
    PMID: 1875928 PMCID: PMC361301
  207. Problems encountered in detecting a targeted gene by the polymerase chain reaction.
    Kim HS, Popovich BW, Shehee WR, Shesely EG, Smithies O.
    Gene. 1991 Jul 22;103(2):227-33.
    PMID: 1889748
  208. Cotransformation and gene targeting in mouse embryonic stem cells.
    Reid LH, Shesely EG, Kim HS, Smithies O.
    Mol Cell Biol. 1991 May;11(5):2769-77.
    PMID: 1850104 PMCID: PMC360052
  209. Homology requirements for unequal crossing over in humans.
    Metzenberg AB, Wurzer G, Huisman TH, Smithies O.
    Genetics. 1991 May;128(1):143-61.
    PMID: 2060774 PMCID: PMC1204444
  210. Correction of a human beta S-globin gene by gene targeting.
    Shesely EG, Kim HS, Shehee WR, Papayannopoulou T, Smithies O, Popovich BW.
    Proc Natl Acad Sci U S A. 1991 May 15;88(10):4294-8.
    PMID: 2034673 PMCID: PMC51645
  211. Testing an “in-out” targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.
    Valancius V, Smithies O.
    Mol Cell Biol. 1991 Mar;11(3):1402-8.
    PMID: 1996101 PMCID: PMC369413
  212. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells.
    Reid LH, Gregg RG, Smithies O, Koller BH.
    Proc Natl Acad Sci U S A. 1990 Jun;87(11):4299-303.
    PMID: 2349238 PMCID: PMC54096
  213. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
    Koller BH, Marrack P, Kappler JW, Smithies O.
    Science. 1990 Jun 8;248(4960):1227-30.
    PMID: 2112266
  214. A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA.
    Kim HS, Smithies O, Maeda N.
    Genomics. 1990 Feb;6(2):260-7.
    PMID: 2307469
  215. Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.
    Henthorn PS, Smithies O, Mager DL.
    Genomics. 1990 Feb;6(2):226-37.
    PMID: 2307466
  216. “Detection of Targeted Gene Modifications by Polymerase Chain Reaction”
    Smithies O, Popovich BW, Kim, HS
    in Polymerase Chain Reaction, editors H.A. Erlich, R. Gibbs, and H.H. Kazazian, Jr.,
    Current Communications in Molecular Biology, Cold Spring Harbor Laboratory Press, pp. 199-203 (1989).
  217. Manipulation of the Mouse Genome by Homologous Recombination.
    Smithies O, Koller BH
    Cold Spring Harbor, Banbury Conference (1989).
  218. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.
    Koller BH, Hagemann LJ, Doetschman T, Hagaman JR, Huang S, Williams PJ, First NL, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 1989 Nov;86(22):8927-31.
    PMID: 2573070 PMCID: PMC298403
  219. Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.
    Koller BH, Smithies O.
    Proc Natl Acad Sci U S A. 1989 Nov;86(22):8932-5.
    PMID: 2682666 PMCID: PMC298404
  220. Replication of plasmid DNA in fertilized Xenopus eggs is sensitive to both the topology and size of the injected template.
    Endean DJ, Smithies O.
    Chromosoma. 1989 Jan;97(4):307-14.
    PMID: 2539959
  221. Targeted mutation of the Hprt gene in mouse embryonic stem cells.
    Doetschman T, Maeda N, Smithies O.
    Proc Natl Acad Sci U S A. 1988 Nov;85(22):8583-7.
    PMID: 3186749 PMCID: PMC282503
  222. Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis.
    Maeda N, Ebert DL, Doers TM, Newman M, Hasler-Rapacz J, Attie AD, Rapacz J, Smithies O.
    Gene. 1988 Oct 30;70(2):213-29.
    PMID: 2905687
  223. Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.
    Lyons KM, Stein JH, Smithies O.
    Genetics. 1988 Sep;120(1):267-78.
    PMID: 2851479 PMCID: PMC1203497
  224. Many protein products from a few loci: assignment of human salivary proline-rich proteins to specific loci.
    Lyons KM, Azen EA, Goodman PA, Smithies O.
    Genetics. 1988 Sep;120(1):255-65.
    PMID: 3220251 PMCID: PMC1203496
  225. Recombinant fragment assay for gene targetting based on the polymerase chain reaction.
    Kim HS, Smithies O.
    Nucleic Acids Res. 1988 Sep 26;16(18):8887-903.
    PMID: 3174435 PMCID: PMC338641
  226. Regulated expression of genes inserted at the human chromosomal beta-globin locus by homologous recombination.
    Nandi AK, Roginski RS, Gregg RG, Smithies O, Skoultchi AI.
    Proc Natl Acad Sci U S A. 1988 Jun;85(11):3845-9.
    PMID: 3375244 PMCID: PMC280316
  227. Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes.
    Saitoh E, Isemura S, Sanada K, Kim HS, Smithies O, Maeda N.
    Biol Chem Hoppe Seyler. 1988 May;369 Suppl:191-7.
    PMID: 3202964
  228. Establishment of hamsterblastocyst-derived embryonic stem (ES) cells.
    Doetschman T, Williams P, Maeda N.
    Dev Biol. 1988 May;127(1):224-7.
    PMID: 3360212
  229. Expression of genes inserted at the human beta-globin locus by homologous recombination.
    Skoultchi AI, Nandi A, Roginski RS, Gregg RG, Smithies O.
    Prog Clin Biol Res. 1987;251:581-94. No abstract available.
    PMID: 2829231
  230.  Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.
    Saitoh E, Kim HS, Smithies O, Maeda N.
    Gene. 1987;61(3):329-38.
    PMID: 3446578
  231. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells.
    Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O.
    Nature. 1987 Dec 10-16;330(6148):576-8.
    PMID: 3683574
  232. Accurate modification of a chromosomal plasmid by homologous recombination in human cells.
    Song KY, Schwartz F, Maeda N, Smithies O, Kucherlapati R.
    Proc Natl Acad Sci U S A. 1987 Oct;84(19):6820-4.
    PMID: 2821545 PMCID: PMC299176
  233. Direct alteration of a gene in the human genome.
    Smithies O.
    J Inherit Metab Dis. 1986;9 Suppl 1:92-7.
    PMID: 3097420
  234. The evolution of multigene families: human haptoglobin genes.
    Maeda N, Smithies O.
    Annu Rev Genet. 1986;20:81-108. Review. No abstract available.
    PMID: 2880559
  235. Targeted modification of human chromosomal genes.
    Gregg RG, Smithies O.
    Cold Spring Harb Symp Quant Biol. 1986;51 Pt 2:1093-9. No abstract available.
    PMID: 3472754
  236. Efficient transformation and frequent single-site, single-copy insertion of DNA can be obtained in mouse erythroleukemia cells transformed by electroporation.
    Boggs SS, Gregg RG, Borenstein N, Smithies O.
    Exp Hematol. 1986 Nov;14(10):988-94.
    PMID: 3464450
  237. Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes.
    Maeda N, McEvoy SM, Harris HF, Huisman TH, Smithies O.
    Proc Natl Acad Sci U S A. 1986 Oct;83(19):7395-9.
    PMID: 2876426 PMCID: PMC386724
  238. A gene deletion ending within a complex array of repeated sequences 3′ to the human beta-globin gene cluster.
    Henthorn PS, Mager DL, Huisman TH, Smithies O.
    Proc Natl Acad Sci U S A. 1986 Jul;83(14):5194-8.
    PMID: 2425363 PMCID: PMC323917
  239. Short gene conversions in the human fetal globin gene region: a by-product of chromosome pairing during meiosis?
    Powers PA, Smithies O.
    Genetics. 1986 Feb;112(2):343-58.
    PMID: 2416635 PMCID: PMC1202705
  240. Gene conversions and their relation to homologous chromosome pairing.
    Smithies O, Powers PA.
    Philos Trans R Soc Lond B Biol Sci. 1986 Jan 29;312(1154):291-302.
    PMID: 2421362
  241. Nucleotide sequence of 16-kilobase pairs of DNA 5′ to the human epsilon-globin gene.
    Li Q, Powers PA, Smithies O.
    J Biol Chem. 1985 Dec 5;260(28):14901-10.
    PMID: 4066658
  242. A Chinese G gamma + (A gamma delta beta)zero thalassemia deletion: comparison to other deletions in the human beta-globin gene cluster and sequence analysis of the breakpoints.
    Mager DL, Henthorn PS, Smithies O.
    Nucleic Acids Res. 1985 Sep 25;13(18):6559-75.
    PMID: 2997715 PMCID: PMC321977
  243. Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination.
    Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS.
    Nature. 1985 Sep 19-25;317(6034):230-4.
    PMID: 2995814
  244. Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.
    Maeda N, Kim HS, Azen EA, Smithies O.
    J Biol Chem. 1985 Sep 15;260(20):11123-30.
    PMID: 2993301
  245. (A gamma delta beta)0-Thalassaemia in Blacks is due to a deletion of 34 kbp of DNA.
    Henthorn PS, Smithies O, Nakatsuji T, Felice AE, Gardiner MB, Reese AL, Huisman TH.
    Br J Haematol. 1985 Feb;59(2):343-56.
    PMID: 2578804
  246. Homologous recombination with DNA introduced into mammalian cells.
    Smithies O, Koralewski MA, Song KY, Kucherlapati RS.
    Cold Spring Harb Symp Quant Biol. 1984;49:161-70. No abstract available.
    PMID: 6597754
  247. Clones from the human gene complex coding for salivary proline-rich proteins.
    Azen E, Lyons KM, McGonigal T, Barrett NL, Clements LS, Maeda N, Vanin EF, Carlson DM,Smithies O.
    Proc Natl Acad Sci U S A. 1984 Sep;81(17):5561-5.
    PMID: 6089212 PMCID: PMC391746
  248. Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.
    Powers PA, Altay C, Huisman TH, Smithies O.
    Nucleic Acids Res. 1984 Sep 25;12(18):7023-34.
    PMID: 6091051 PMCID: PMC320140
  249. Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA.
    Kucherlapati RS, Eves EM, Song KY, Morse BS, Smithies O.
    Proc Natl Acad Sci U S A. 1984 May;81(10):3153-7.
    PMID: 6328502 PMCID: PMC345239
  250. Duplication within the haptoglobin Hp2 gene.
    Maeda N, Yang F, Barnett DR, Bowman BH, Smithies O.
    Nature. 1984 May 10-16;309(5964):131-5.
    PMID: 6325933
  251. A comprehensive set of sequence analysis programs for the VAX.
    Devereux J, Haeberli P, Smithies O.
    Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):387-95.
    PMID: 6546423 PMCID: PMC321012
  252. Unexpected relationships between four large deletions in the human beta-globin gene cluster.
    Vanin EF, Henthorn PS, Kioussis D, Grosveld F, Smithies O.
    Cell. 1983 Dec;35(3 Pt 2):701-9.
    PMID: 6652684
  253. Coordinate modulation of transfected HSV thymidine kinase and human globin genes.
    Roginski RS, Skoultchi AI, Henthorn P, Smithies O, Hsiung N, Kucherlapati R.
    Cell. 1983 Nov;35(1):149-55.
    PMID: 6313221
  254. Recombination and balanced chromosome polymorphism suggested by DNA sequences 5′ to the human delta-globin gene.
    Maeda N, Bliska JB, Smithies O.
    Proc Natl Acad Sci U S A. 1983 Aug;80(16):5012-6.
    PMID: 6308666 PMCID: PMC384178
  255. The control of globin and other eukaryotic genes.
    Smithies O.
    J Cell Physiol Suppl. 1982;1:137-43.
    PMID: 6175650
  256. Human globin psi B2 is not a globin-related sequence.
    Shen SH, Smithies O.
    Nucleic Acids Res. 1982 Dec 11;10(23):7809-18.
    PMID: 6897566 PMCID: PMC327047
  257. Introduction and expression of a fetal human globin gene in mouse fibroblasts.
    Hsiung N, Roginski RS, Henthorn P, Smithies O, Kucherlapati R, Skoultchi AI.
    Mol Cell Biol. 1982 Apr;2(4):401-11.
    PMID: 6180305 PMCID: PMC369804
  258. Co-Evolution and Control of Globin Genes.
    Smithies O, Blechl AE, Shen S, Slightom JL, Vanin EF
    39th Symposium for the Society for Developmental Biology.  In Levels of Genetic Control in Development.
    Subtlelny and U. K. Abbot, editors.  Alan R. Liss, New York.  Pp. 185-200 (1981).
  259. Co-Evolution and Control of Globin Genes.
    Smithies O, Blechl AE, Shen S, Slightom JL, Vanin EF
    In Organization and Expression of Globin Genes. G. Stamatoyannopoulos and A. W. Nienhuis, Editors.
    Alan R. Liss, New York.  Pp. 101-116 (1981).
  260. Base substitutions, length differences and DNA strand asymmetries in the human G gamma and A gamma fetal globin gene region.
    Smithies O, Engels WR, Devereux JR, Slightom JL, Shen S.
    Cell. 1981 Nov;26(3 Pt 1):345-53.
    PMID: 6173131
  261. A history of the human fetal globin gene duplication.
    Shen SH, Slightom JL, Smithies O.
    Cell. 1981 Oct;26(2 Pt 2):191-203.
    PMID: 7332928
  262. Partial amino acid sequences of human and dog post-gamma globulins.
    Poulik MD, Shinnick CS, Smithies O.
    Mol Immunol. 1981 Jun;18(6):569-72. No abstract available.
    PMID: 7311984
  263. Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.
    Slightom JL, Blechl AE, Smithies O.
    Cell. 1980 Oct;21(3):627-38.
    PMID: 7438203
  264. The structure and evolution of the human beta-globin gene family.
    Efstratiadis A, Posakony JW, Maniatis T, Lawn RM, O’Connell C, Spritz RA, DeRiel JK, Forget BG, Weissman SM, Slightom JL, Blechl AE, Smithies O, Baralle FE, Shoulders CC, Proudfoot NJ.
    Cell. 1980 Oct;21(3):653-68.
    PMID: 6985477
  265. A mouse alpha-globin-related pseudogene lacking intervening sequences.
    Vanin EF, Goldberg GI, Tucker PW, Smithies O.
    Nature. 1980 Jul 17;286(5770):222-6.
    PMID: 6250049
  266. Genomic Clones and Unfractionated DNA.
    Smithies O, Slightom JL, Tucker PW, Blattner FR.
    From Gene to Protein:  Information Transfer in Normal and Abnormal Cells.
    The Eleventh Miami Winter Symposium, pp. 167-186 (1979).
  267. Partial amino acid sequences of rabbit and rat beta 2-microglobulins.
    Poulik MD, Smithies O.
    Mol Immunol. 1979 Sep;16(9):731-4. No abstract available.
    PMID: 93696
  268. Amino Acid Sequence Determination of Proteins Labelled in Tritium Gas by Microwave Discharge.
    Wessels BW, McKean DJ, Lien NC, Shinnick C, Deluca PM, Smithies O.
    Radiation Research 74:35-50 (1978).
  269. Segregation of some chromosomal proteins during cell replication.
    Freedlender EF, Taichman L, Smithies O.
    Cold Spring Harb Symp Quant Biol. 1978;42 Pt 1:417-20. No abstract available.
    PMID: 277355
  270. Cloning human fetal gamma globin and mouse alpha-type globin DNA: characterization and partial sequencing.
    Smithies O, Blechl AE, Denniston-Thompson K, Newell N, Richards JE, Slightom JL, Tucker PW, Blattner FR.
    Science. 1978 Dec 22;202(4374):1284-9.
    PMID: 725604
  271. Cloning human fetal gamma globin and mouse alpha-type globin DNA: preparation and screening of shotgun collections.
    Blattner FR, Blechl AE, Denniston-Thompson K, Faber HE, Richards JE, Slightom JL, Tucker PW,Smithies O.
    Science. 1978 Dec 22;202(4374):1279-84.
    PMID: 725603
  272. Unusual genes at the aminoterminus of human immunoglobulin variants.
    Frangione B, Franklin EC, Smithies O.
    Nature. 1978 Jun 1;273(5661):400-1. No abstract available.
    PMID: 96346
  273. Protein Sequencing with Radioisotopes.
    Walker ID, Smithies O, Ballou B, Freedlender EF, Shinnick CJ.
    Trends in Biochemical Sciences 2(8):179-184 (1977).
  274. A simplified chloral hydrate electrophoresis system for analysis of biological membranes.
    Ballou B, Smithies O.
    Anal Biochem. 1977 Jun;80(2):616-23. No abstract available.
    PMID: 889098
  275. Nonrandom distribution of chromosomal proteins during cell replication.
    Freedlender EF, Taichman L, Smithies O.
    Biochemistry. 1977 May 3;16(9):1802-8.
    PMID: 557988
  276. Charon phages: safer derivatives of bacteriophage lambda for DNA cloning.
    Blattner FR, Williams BG, Blechl AE, Denniston-Thompson K, Faber HE, Furlong L, Grunwald DJ, Kiefer DO, Moore DD, Schumm JW, Sheldon EL, Smithies O.
    Science. 1977 Apr 8;196(4286):161-9.
    PMID: 847462
  277. Assignment of the gene for beta-2-microglobulin to human chromosome 15.
    Kucherlapati RS, Faber HE, Poulik MD, Ruddle FH, Smithies O.
    Cytogenet Cell Genet. 1976;16(1-5):178-80. No abstract available.
    PMID: 61837
  278. HLA membrane antigens: sequencing by intrinsic radioactivity.
    Ballou B, McKean DJ, Freedlender EF, Smithies O.
    Proc Natl Acad Sci U S A. 1976 Dec;73(12):4487-91.
    PMID: 794879 PMCID: PMC431511
  279. beta2-microglobulin locus on human chromosome 15.
    Faber HE, Kucherlapati RS, Poulik MD, Ruddle FH, Smithies O.
    Somatic Cell Genet. 1976 Mar;2(2):141-53.
    PMID: 69326
  280. Low molecular weight urinary proteins. I. Partial amino acid sequences of the retinol-binding proteins of man and dog.
    Poulik MD, Farrah D, Malek GH, Shinnick CJ, Smithies O.
    Biochim Biophys Acta. 1975 Dec 15;412(2):326-34.
    PMID: 1103975
  281. Hybridization of labeled RNA to DNA in agarose gels.
    Shinnick TM, Lund E, Smithies O, Blattner FR.
    Nucleic Acids Res. 1975 Oct;2(10):1911-29.
    PMID: 1103090 PMCID: PMC343556
  282. Immunoglobulin genes: arranged in tandem or in parallel?
    Smithies O.
    Cold Spring Harb Symp Quant Biol. 1974;38:725-37. No abstract available.
    PMID: 4524785
  283.  Letter: Recombinant DNA molecules.
    Smithies O.
    Genetics. 1974 Aug;77(4):819-20. No abstract available.
    PMID: 4608059 PMCID: PMC1213170
  284. Amino acid sequence determination with radioactive proteins.
    McKean DJ, Peters EH, Waldby JI, Smithies O.
    Biochemistry. 1974 Jul 16;13(15):3048-51. No abstract available.
    PMID: 4841052
  285. Components of the major urinary protein complex of inbred mice: determination of NH2-terminal sequences and comparison with homologous components from wild mice.
    Finlayson JS, Potter M, Shinnick CS, Smithies O.
    Biochem Genet. 1974 Apr;11(4):325-35. No abstract available.
    PMID: 4838000
  286. Hinge-region deletion localized in the IgG-globulin Mcg.
    Fett JW, Deutsch HF, Smithies O.
    Immunochemistry. 1973 Feb;10(2):115-8. No abstract available.
    PMID: 4727433
  287. Dog homologue of human 2 -microglobulin.
    Smithies O, Poulik MD.
    Proc Natl Acad Sci U S A. 1972 Oct;69(10):2914-7.
    PMID: 4507614 PMCID: PMC389673
  288. Probable identity of tissue specific histone with encephalitogenic protein.
    Kornguth SE, Kozel LR, Smithies O.
    Nat New Biol. 1972 May 10;237(71):49-50. No abstract available.
    PMID: 4503744
  289. Initiation of protein synthesis at an unusual position in an immunoglobulin gene?
    Smithies O, Poulik MD.
    Science. 1972 Jan 14;175(4018):187-9.
    PMID: 5008437
  290. Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac.
    Smithies O, Gibson D, Fanning EM, Goodfliesh RM, Gilman JG, Ballantyne DL.
    Biochemistry. 1971 Dec 21;10(26):4912-21. No abstract available.
    PMID: 5134536
  291. Partial amino acid sequences of two urinary proteins characteristic of tubular proteinemia.
    Poulik MD, Ballantyne DL, Shinnick CJ, Smithies O.
    J Lab Clin Med. 1971 Nov;78(5):822. No abstract available.
    PMID: 5128865
  292. Heterogeneity of normal human immunoglobulin light chains. Nonallelic variation in the constant region of lambda chains.
    Gibson D, Levanon M, Smithies O.
    Biochemistry. 1971 Aug 3;10(16):3114-22. No abstract available.
    PMID: 4108342
  293. Deletions in immunoglobulin polypeptide chains as evidence for breakage and repair in DNA.
    Smithies O, Gibson DM, Fanning EM, Percy ME, Parr DM, Connell GE.
    Science. 1971 May 7;172(3983):574-7.
    PMID: 4101951
  294. Phosphorylation and synthesis of histones in regenerating rat liver.
    Sung MT, Dixon GH, Smithies O.
    J Biol Chem. 1971 Mar 10;246(5):1358-64. No abstract available.
    PMID: 5547589
  295. Pathways through networks of branched DNA.
    Smithies O.
    Science. 1970 Aug 28;169(3948):882-3.
    PMID: 5432585
  296. Differential elution of histones from gel-trapped nuclei.
    Sung M, Smithies O.
    Biopolymers. 1969;7(1):39-58. No abstract available.
    PMID: 5772420
  297. Linkage Relationships in Normal Light Chains.
    Smithies O, Gibson D, Levanon M.
    In: Symposium on Developmental Aspects of Antibody Formation and Structure, Prague, Czechoslovakia,
    Vol. I, pp. 339-345 (1969).
  298. The Variability of Antibodies.
    Smithies O.
    Proc. XXII Intern Congress of Genetics 3:167-176 (1969).
  299. High-voltage starch-gel electrophoresis in the study of post-albumin proteins and C’3(beta 1-c-globulin) polymorphism.
    Azen EA, Smithies O, Hiller O.
    Biochem Genet. 1969 Jun;3(3):215-28. No abstract available.
    PMID: 5409404
  300. Genetic Aspects of the Immune System.
    Smithies O.
    In: Child Care in Health and Disease.  Year Book Medical Publishers pp. 364-372 (1968).
  301. Perspectives: Mutation and Selection in the Immune System.
    Smithies O.
    Regulation of Antibody Response, B. Cinader, Ed., 363-375 (1968).
  302. Genetic polymorphism of C’3(beta1C-globulin) in human serum.
    Azen EA, Smithies O.
    Science. 1968 Nov 22;162(3856):905-7.
    PMID: 4176438
  303.  Genetics of variability.
    Smithies O.
    Brookhaven Symp Biol. 1968 Jun;21(1):243-58. No abstract available.
    PMID: 4180687
  304. Fetal hemoglobin variants in mice.
    Gilman JG, Smithies O.
    Science. 1968 May 24;160(3830):885-6.
    PMID: 5647833
  305. Improvement of the microtiter hemagglutination method.
    Wegmann TG, Smithies O.
    Transfusion. 1968 Jan-Feb;8(1):47. No abstract available.
    PMID: 4965859
  306. Smithies, O.  The Genetic Basis of Antibody Variability.
    Smithies O.
    In:  Cold Spring Harbor Symposia on Quantitative Biology, Vol. XXXII pp. 161-168 (1967).
  307. Antibody-producing cells in division.
    Claflin AJ, Smithies O.
    Science. 1967 Sep 29;157(3796):1561-2. No abstract available.
    PMID: 5341450
  308. Antibody variability. Somatic recombination between the elements of “antibody gene pairs” may explain antibody variability.
    Smithies O.
    Science. 1967 Jul 21;157(3786):267-73. Review.
    PMID: 4165728
  309. Acidic Buffer Systems for Urea-Starch Gel Electrophoresis.
    Azen EA, Smithies O, Nazhat RA.
    Lab. and Clin. Med. 67(4):650-659 (1966).
  310. A Simple Hemagglutination System Requiring Small Amounts of Red Cells and Antibodies.
    Wegmann T, Smithies O.
    Transfusion 6:67 (1966).
  311. [Nomenclature of genetically determined characteristics of human immunoglobulins].
    Ceppellini R, Dray S, Fahey JL, Franklin EC, Fudenberg H, Gell PG, Goodman HC, Grubb R, Harboe M, Kirk RL, Oudin J, Ropartz C, Smithies O, Steinberg AG, Trnka Z.
    Humangenetik. 1966;2(3):317-22. German. No abstract available.
    PMID: 4168284
  312. Antibody responses in bursa-deficient chickens.
    Claflin AJ, Smithies O, Meyer RK.
    J Immunol. 1966 Nov;97(5):693-9. No abstract available.
    PMID: 4959015
  313. Gene action in the human haptoglobins. I. Dissociation into constituent polypeptide chains.
    Smithies O, Connell GE, Dixon GH.
    J Mol Biol. 1966 Nov 14;21(2):213-24. No abstract available.
    PMID: 5972461
  314. Gene action in the human haptoglobins. II. Isolation and physical characterization of alpha polypeptide chains.
    Connell GE, Smithies O, Dixon GH.
    J Mol Biol. 1966 Nov 14;21(2):225-9. No abstract available.
    PMID: 5972462
  315. Somatic mutations and proteins.
    Smithies O.
    Proc R Soc Lond B Biol Sci. 1966 Mar 22;164(995):320-7. Review. No abstract available.
    PMID: 4379521
  316. Characterization of genetic variants of blood proteins.
    Smithies O.
    Bibl Haematol. 1965;23:1175-7. No abstract available.
    PMID: 4957215
  317. Chromosomal rearrangements and protein structure.
    Smithies O.
    Bibl Haematol. 1965;23:373-4. No abstract available.
    PMID: 5867127
  318. Disulfide-bond cleavage and formation in proteins.
    Smithies O.
    Science. 1965 Dec 17;150(3703):1595-8.
    PMID:5866656
  319. Antibody Induction and Tolerance.
    Smithies O.
    Science. 1965 Jul 9;149(3680):151-6. No abstract available.
    PMID: 17734491
  320. CHARACTERIZATION OF GENETIC VARIANTS OF BLOOD PROTEINS.
    SMITHIES O.
    Vox Sang. 1965 May-Jun;10:359-62. No abstract available.
    PMID: 14332941
  321. STARCH-GEL ELECTROPHORESIS OF ERYTHROCYTE STROMA.
    AZEN EA, ORR S, SMITHIES O.
    J Lab Clin Med. 1965 Mar;65:440-9. No abstract available.
    PMID: 14261325
  322. CHROMOSOMAL REARRANGEMENTS AND PROTEIN STRUCTURE.
    SMITHIES O.
    Cold Spring Harb Symp Quant Biol. 1964;29:309-19. No abstract available.
    PMID: 14280817
  323. GEL ELECTROPHORESIS: INTRODUCTORY REMARKS.
    SMITHIES O.
    Ann N Y Acad Sci. 1964 Dec 28;121:309. No abstract available.
    PMID: 14240531
  324. STARCH-GEL ELECTROPHORESIS.
    SMITHIES O.
    Metabolism. 1964 Oct;13:SUPPL:974-84. No abstract available.
    PMID: 14228776
  325. Smithies, O.  Protein Variations in Man.
    Smithies O.
    In: Proc. XI International Congress of Genetics.  Pergamon Press pp. 897-901 (1963).
  326. LACTIC DEHYDROGENASE: GENETIC CONTROL IN MAN.
    NANCE WE, CLAFLIN A, SMITHIES O.
    Science. 1963 Nov 22;142(3595):1075-7.
    PMID: 14068226
  327. GAMMA-GLOBULIN VARIABILITY: A GENETIC HYPOTHESIS.
    SMITHIES O.
    Nature. 1963 Sep 28;199:1231-6. No abstract available.
    PMID: 14074584
  328. New haptoglobin alleles: a prediction confirmed.
    NANCE WE, SMITHIES O.
    Nature. 1963 Jun 1;198:869-70. No abstract available.
    PMID: 13937541
  329. Transferrin Variation in Columbidae.
    Mueller JO, Smithies O, Irwin MR.
    Genetics. 1962 Oct;47(10):1385-92. No abstract available.
    PMID: 17248132 PMCID: PMC1210289
  330. Chromosomal rearrangements and the evolution of haptoglobin genes.
    SMITHIES O, CONNELL GE, DIXON GH.
    Nature. 1962 Oct 20;196:232-6. No abstract available.
    PMID: 13989613
  331. Molecular size and starch-gel electrophoresis.
    SMITHIES O.
    Arch Biochem Biophys. 1962 Sep;Suppl 1:125-31. No abstract available.
    PMID: 13989614
  332. Frequencies of blood groups, serum haptoglobins and levels of slow alpha2-globulin in diabetics and their relatives.
    SIMPSON NE, GUNSON HH, SMITHIES O.
    Diabetes. 1962 Jul-Aug;11:329-33. No abstract available.
    PMID: 13913229
  333. Inheritance of haptoglobin subtypes.
    SMITHIES O, CONNELL GE, DIXON GH.
    Am J Hum Genet. 1962 Mar;14:14-21. No abstract available.
    PMID: 13914473 PMCID: PMC1932187
  334. Subdivision of the three common haptoglobin types based on ‘hidden’ diffrences.
    CONNELL GE, DIXON GH, SMITHIES O.
    Nature. 1962 Feb 3;193:505-6. No abstract available.
    PMID: 13880879
  335. Haptoglobins.
    Smithies O.
    In: Transactions of Macy Foundation Conference on Genetics.  pp. 129-136 (1960).
  336. The occurrence of two unusual serum protein phenotypes in a single pedigree.
    HARRIS H, LAWLER SD, ROBSON EB, SMITHIES O.
    Ann Hum Genet. 1960 Apr;24:63-9. No abstract available.
    PMID: 14399953
  337. Biochemical Aspects of the Inherited Variations in Human Serum Haptoglobins and Transferrins.
    Smithies O, Connell GE.
    In:  Biochemistry of Human Genetics.  Ciba Symposium, Churchill (London) pp. 178-189 (1959).
  338. Zone electrophoresis in starch gels and its application to studies of serum proteins.
    SMITHIES O.
    Adv Protein Chem. 1959;14:65-113. No abstract available.
    PMID: 13832188
  339. Serum transferrins.
    GIBLETT ER, HICKMAN CG, SMITHIES O.
    Nature. 1959 Jun 6;183(4675):1589-90. No abstract available.
    PMID: 13666824
  340. Human haptoglobins: estimation and purification.
    CONNELL GE, SMITHIES O.
    Biochem J. 1959 May;72(1):115-21. No abstract available.
    PMID: 13651145 PMCID: PMC1196890
  341. The genetic control of transferrins in humans.
    SMITHIES O, HILLER O.
    Biochem J. 1959 May;72(1):121-6. No abstract available.
    PMID: 13651146 PMCID: PMC1196891
  342. An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals.
    SMITHIES O.
    Biochem J. 1959 Mar;71(3):585-7. No abstract available.
    PMID: 13638269 PMCID: PMC1196836
  343. The Serum ß-globulin System in Humans.
    Smithies O.
    Proc. X International Congress of Genetics 2:266 (1958).
  344.  Genetic control of some human serum beta-globulins.
    HORSFALL WR, SMITHIES O.
    Science. 1958 Jul 4;128(3314):35. No abstract available.
    PMID: 13555927
  345. Inherited Variations in the Serum Proteins of Cattle.
    Smithies O, Hickman CG.
    Genetics. 1958 May;43(3):374-85. No abstract available.
    PMID: 17247763 PMCID: PMC1209887
  346. Comparison and combination of the starch-gel and filter-paper electrophoretic methods applied to human sera: two-dimensional electrophoresis.
    POULIK MD, SMITHIES O.
    Biochem J. 1958 Apr;68(4):636-43. No abstract available.
    PMID: 13522673 PMCID: PMC1200410
  347. Third allele at the serum beta-globulin locus in humans.
    SMITHIES O.
    Nature. 1958 Apr 26;181(4617):1203-4. No abstract available.
    PMID: 13541421
  348. Evidence for Inherited Variations in the Serum Proteins of Cattle.
    Hickman G, Smithies O.
    Proc. Genetics Soc. Canada. 2:39 (1957).
  349. Variations in human serum beta-globulins.
    SMITHIES O.
    Nature. 1957 Dec 28;180(4600):1482-3. No abstract available.
    PMID: 13493574
  350. Zone electrophoresis of cabbage enzymes in starch gels.
    DIXON GH, SMITHIES O.
    Biochim Biophys Acta. 1957 Jan;23(1):198-9. No abstract available.
    PMID: 13412698
  351. Notation for serum-protein groups and the genes controlling their inheritance.
    SMITHIES O, WALKER NF.
    Nature. 1956 Sep 29;178(4535):694-5. No abstract available.
    PMID: 13369501
  352. Two-dimensional electrophoresis of serum proteins.
    SMITHIES O, POULIK MD.
    Nature. 1956 Jun 2;177(4518):1033. No abstract available.
    PMID: 13322019
  353. Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults.
    SMITHIES O.
    Biochem J. 1955 Dec;61(4):629-41. No abstract available.
    PMID: 13276348 PMCID: PMC1215845
  354. Genetic control of some serum proteins in normal humans.
    SMITHIES O, WALKER NF.
    Nature. 1955 Dec 31;176(4496):1265-6. No abstract available.
    PMID: 13321879
  355. Grouped variations in the occurrence of new protein components in normal human serum.
    SMITHIES O.
    Nature. 1955 Feb 12;175(4450):307-8. No abstract available.
    PMID: 13235885
  356. The application of four methods for assessing protein homogeneity to crystalline beta-lactoglobulin: an anomaly in phase rule solubility tests.
    SMITHIES O.
    Biochem J. 1954 Sep;58(1):31-8. No abstract available.
    PMID: 13198844 PMCID: PMC1269835
  357. A dynamic osmometer for accurate measurements on small quantities of material: osmotic pressures of isoelectric beta-lactoglobulin solutions.
    SMITHIES O.
    Biochem J. 1953 Aug;55(1):57-67. No abstract available.
    PMID: 13093617 PMCID: PMC1269135
  358. Some thermodynamic and kinetic aspects of metabolic phosphorylation.
    OGSTON AG, SMITHIES O.
    Physiol Rev. 1948 Jul;28(3):283-303. No abstract available.
    PMID: 18874569